Dito Oktawijaya Pratama; Brahmana Askandar Tjokroprawiro; Lulus Handayani
Abstract
The aims of this article was to determine the correlation among clinical characteristics and therapeutic treatments on disease free survival (DFS) and 5 years survival in stage III-IV ...
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The aims of this article was to determine the correlation among clinical characteristics and therapeutic treatments on disease free survival (DFS) and 5 years survival in stage III-IV cervical cancer patients with limited radiotherapy facility. This was a retrospective cohort study of all patients admitted to our hospital from 2016-2022. Data on clinical characteristics were collected from medical records. Statistical analysis was performed to determine the relationship between therapeutic treatments and clinical characteristics, including age, histopathology, tumor size, and patient outcomes. Total sample was 216 patients. Patient with tumor size <6 cm had better survival rate and DFS than tumor size >6 cm (24 months vs. 21 months and 22 months vs. 12 months), radiotherapy waiting list <4 months showed better survival rate and DFS than patients who waited >4 months (33 months vs. 24 months and 24 months vs. 16 months), patients who received chemotherapy while waiting for radiotherapy had better survival rate and DFS than patients who did not (24 months vs. 10 months and 22 months vs. 10 months), and patients who continued ER AFL had better survival rate and DFS than patients who just received ER (44 months vs. 24 months and 34 months vs. 16 months). Tumor size, radiotherapy waiting list, chemotherapy administration, and type of radiotherapy are the most significant factors for outcome patients of stage III-IV cervical cancer.
